Strain - Detail
| Request |
 |
|
|---|---|---|
| NBRP ID | S00342 | |
| Strain Name | rasC- | |
| Strain Summary | rasC null in AX2 | |
| Strain Descriptor | rasC-/AX2 | |
| Systematic Name | DBS0236853 | |
| Species | Dictyostelium discoideum | |
| Category | Recombinant | |
| Parental Strain | AX2 (GW) | |
| Mutagenesis Method | homologous recombination | |
| Mutagenesis Detail | rasC::bsr | |
| Associated Gene | rasC | |
| Foreign Gene | bsR | |
| Genotype | axeA2, axeB2, axeC2, bsR, rasC-[rasC::bsr] | |
| Phenotype | axenic, blasticidin resistant, drug resistant, null mutant | |
| Axenic Growth | Y | |
| Viable Spore Formation | NG | |
| References |
Lim CJ, Spiegelman GB, Weeks G.
RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation. EMBO J (2001) 20(16) 4490-9 [PubMed ID = 11500376] [RRC reference] Wessels D, Brincks R, Kuhl S, Stepanovic V, Daniels KJ, Weeks G, Lim CJ, Spiegelman G, Fuller D, Iranfar N, Loomis WF, Soll DR. RasC plays a role in transduction of temporal gradient information in the cyclic-AMP wave of Dictyostelium discoideum. Eukaryot Cell (2004) 3(3) 646-62 [PubMed ID = 15189986] [RRC reference] Kamimura Y, Miyanaga Y, Ueda M. Heterotrimeric G-protein shuttling via Gip1 extends the dynamic range of eukaryotic chemotaxis. Proc Natl Acad Sci U S A (2016) 113(16) 4356-61 [PubMed ID = 27044073] [RRC reference] |
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| Other Information | ||
| Depositor | Satoshi Sawai | |
| Position | ||
| Source | DSC | |
| Use Condition | A | |
| DSC | DBS0236853 | |
| Remarks | ||
| Images | ||
| Sequence | ||
