Strain - Detail
| Request |
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| NBRP ID | S90284 | |
| Strain Name | B1B11, lvsB-null | |
| Strain Summary | lvsB null mutant (Large Volume Sphere B) | |
| Strain Descriptor | lvsB- | |
| Systematic Name | B1B11 | |
| Species | Dictyostelium discoideum | |
| Category | Recombinant | |
| Parental Strain | NC4A2 | |
| Mutagenesis Method | homologous recombination | |
| Mutagenesis Detail | endogenous deletion, lvsB-KO | |
| Associated Gene | lvsB | |
| Foreign Gene | bsR | |
| Genotype | axe,lvsB-[lvsB-KO],bsR | |
| Phenotype | lvsB-KO | |
| Axenic Growth | Y | |
| Viable Spore Formation | OK | |
| References |
Cornillon S, Dubois A, Brückert F, Lefkir Y, Marchetti A, Benghezal M, De Lozanne A, Letourneur F, Cosson P.
Two members of the beige/CHS (BEACH) family are involved at different stages in the organization of the endocytic pathway in Dictyostelium. J Cell Sci (2002) 115(Pt 4) 737-44 [PubMed ID = 11865029] [RRC reference] Harris E, Wang N, Wu Wl WL, Weatherford A, De Lozanne A, Cardelli J. Dictyostelium LvsB mutants model the lysosomal defects associated with Chediak-Higashi syndrome. Mol Biol Cell (2002) 13(2) 656-69 [PubMed ID = 11854420] [RRC reference] Wang N, Wu WI, De Lozanne A. BEACH family of proteins: phylogenetic and functional analysis of six Dictyostelium BEACH proteins. J Cell Biochem (2002) 86(3) 561-70 [PubMed ID = 12210762] [RRC reference] |
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| Other Information | ||
| Depositor | DSC | |
| Position | ||
| Source | A. De Lozanne | |
| Use Condition | A | |
| DSC | DBS0236521 | |
| Remarks | ||
| Images | ||
| Sequence | ||

