Strain - Detail
| Request |
 |
|
|---|---|---|
| NBRP ID | S90291 | |
| Strain Name | cnx-, 1-2-26 | |
| Strain Summary | cnxA (calnexin) null mutant | |
| Strain Descriptor | cnxA- | |
| Systematic Name | HG1770 | |
| Species | Dictyostelium discoideum | |
| Category | Recombinant | |
| Parental Strain | AX2-214 (DBS0235534) | |
| Mutagenesis Method | homologous recombination | |
| Mutagenesis Detail | endogenous deletion, pBsr2-cnx | |
| Associated Gene | cnxA | |
| Foreign Gene | bsR | |
| Genotype | axeA2,axeb2,axeC2, cnxA-[pBsr2-cnx],bsR | |
| Phenotype | blasticidin resistant, axenic, null mutant | |
| Axenic Growth | Y | |
| Viable Spore Formation | OK | |
| References |
Müller-Taubenberger A, Lupas AN, Li H, Ecke M, Simmeth E, Gerisch G.
Calreticulin and calnexin in the endoplasmic reticulum are important for phagocytosis. EMBO J (2001) 20(23) 6772-82 [PubMed ID = 11726513] [RRC reference] Fajardo M, Schleicher M, Noegel A, Bozzaro S, Killinger S, Heuner K, Hacker J, Steinert M. Calnexin, calreticulin and cytoskeleton-associated proteins modulate uptake and growth of Legionella pneumophila in Dictyostelium discoideum. Microbiology (Reading) (2004) 150(Pt 9) 2825-2835 [PubMed ID = 15347742] [RRC reference] |
|
| Other Information | ||
| Depositor | DSC | |
| Position | ||
| Source | G. Gerisch | |
| Use Condition | A | |
| DSC | DBS0236189 | |
| Remarks | ||
| Images | ||
| Sequence | ||
