株リソース - 詳細
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NBRP ID | S00335 | |
Strain Name | Akt/PKB null, PKB- | |
Strain Summary | pkbA null mutant | |
Strain Descriptor | pkbA- | |
Systematic Name | DBS0236784 | |
Species | Dictyostelium discoideum | |
Category | Recombinant | |
Parental Strain | KAX3 | |
Mutagenesis Method | homologous recombination | |
Mutagenesis Detail | pkb-bsR (bsR cassette at position 520 of Akt/PKB ORF) | |
Associated Gene | pkbA | |
Foreign Gene | bsR | |
Genotype | axeA1,axeB1,axeC1,pkbA-[pkb-bsR],bsR | |
Phenotype | axenic,blasticidin resistant, null mutant | |
Axenic Growth | Y | |
Viable Spore Formation | ||
References |
Chung CY, Potikyan G, Firtel RA.
Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa. Mol Cell (2001) 7(5) 937-47 [PubMed ID = 11389841] [RRC文献情報] Meili R, Ellsworth C, Lee S, Reddy TB, Ma H, Firtel RA. Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO J (1999) 18(8) 2092-105 [PubMed ID = 10205164] [RRC文献情報] |
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Other Information | ||
Depositor | Satoshi Sawai | |
Position | ||
Source | DSC | |
Use Condition | A | |
DSC | DBS0236784 | |
Remarks | ||
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