Strain - Detail

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NBRP ID S00414
Strain Name AD63, vig9, V1G9
Strain Summary lvsA null mutant (large volume sphere A)
Strain Descriptor lvsA-
Systematic Name AD63
Species Dictyostelium discoideum
Category Recombinant
Parental Strain DH1
Mutagenesis Method homologous recombination
Mutagenesis Detail pEKKO-1 (lvsA fragments in pRHI30)
Associated Gene lvsA 
Foreign Gene
Genotype axeA1, axeB1, axeC1, lvsA-[pEKKO-1],pyr5-6-[pRG24],ura+
Phenotype axenic, null mutant
Axenic Growth Y
Viable Spore Formation NO
References Kwak E, Gerald N, Larochelle DA, Vithalani KK, Niswonger ML, Maready M, De Lozanne A.
LvsA, a protein related to the mouse beige protein, is required for cytokinesis in Dictyostelium.
Mol. Biol. Cell  (1999)  10(12)   4429-39  
[PubMed ID = 10588668]  [RRC reference
Landré JB, Hewett PW, Olivot JM, Friedl P, Ko Y, Sachinidis A, Moenner M.
Human endothelial cells selectively express large amounts of pancreatic-type ribonuclease (RNase 1).
J. Cell. Biochem.  (2002)  86(3)   540-52  
[PubMed ID = 12210760]  [RRC reference
Other Information
Depositor DSC
Source A. Lozanne
Use Condition A
DSC DBS0236519