Strain - Detail

NBRP ID S90284
Strain Name B1B11, lvsB-null
Strain Summary lvsB null mutant (Large Volume Sphere B)
Strain Descriptor lvsB-
Systematic Name B1B11
Species Dictyostelium discoideum
Category Recombinant
Parental Strain NC4A2
Mutagenesis Method homologous recombination
Mutagenesis Detail endogenous deletion, lvsB-KO
Associated Gene lvsB 
Foreign Gene bsR
Genotype axe,lvsB-[lvsB-KO],bsR
Phenotype lvsB-KO
Axenic Growth Y
Viable Spore Formation OK
References Cornillon S, Dubois A, Brückert F, Lefkir Y, Marchetti A, Benghezal M, De Lozanne A, Letourneur F, Cosson P.
Two members of the beige/CHS (BEACH) family are involved at different stages in the organization of the endocytic pathway in Dictyostelium.
J Cell Sci  (2002)  115(Pt 4)   737-44  
[PubMed ID = 11865029]  [RRC reference
Harris E, Wang N, Wu Wl WL, Weatherford A, De Lozanne A, Cardelli J.
Dictyostelium LvsB mutants model the lysosomal defects associated with Chediak-Higashi syndrome.
Mol Biol Cell  (2002)  13(2)   656-69  
[PubMed ID = 11854420]  [RRC reference
Wang N, Wu WI, De Lozanne A.
BEACH family of proteins: phylogenetic and functional analysis of six Dictyostelium BEACH proteins.
J Cell Biochem  (2002)  86(3)   561-70  
[PubMed ID = 12210762]  [RRC reference
Other Information
Depositor DSC
Source A. De Lozanne
Use Condition A
DSC DBS0236521