Strain - Detail

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NBRP ID S90285
Strain Name clc-
Strain Summary clathrin light chain (clc) null mutant
Strain Descriptor clc-
Systematic Name clcA-, 2A1, DdCLC-null
Species Dictyostelium discoideum
Category Recombinant
Parental Strain NC4A2
Mutagenesis Method homologous recombination
Mutagenesis Detail endogenous deletion, pBSIIBsrΔclc
Associated Gene clc 
Foreign Gene bsR
Genotype axe, matA1, clc-, bsR
Phenotype blasticidin resistant, axenic, null mutant
Axenic Growth Y
Viable Spore Formation NO
References Wang J, Virta VC, Riddelle-Spencer K, O'Halloran TJ.
Compromise of clathrin function and membrane association by clathrin light chain deletion.
Traffic  (2003)  4(12)   891-901  
[PubMed ID = 14617352]  [RRC reference
Clarke M, Müller-Taubenberger A, Anderson KI, Engel U, Gerisch G.
Mechanically induced actin-mediated rocketing of phagosomes.
Mol. Biol. Cell  (2006)  17(11)   4866-75  
[PubMed ID = 16971511]  [RRC reference
Other Information
Depositor DSC
Source T. OHalloran
Use Condition A
DSC DBS0235601
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