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Strain - Detail

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NBRP ID S90291
Strain Name cnx-, 1-2-26
Strain Summary cnxA (calnexin) null mutant
Strain Descriptor cnxA-
Systematic Name HG1770
Species Dictyostelium discoideum
Category Recombinant
Parental Strain AX2-214 (DBS0235534)
Mutagenesis Method homologous recombination
Mutagenesis Detail endogenous deletion, pBsr2-cnx
Associated Gene cnxA 
Foreign Gene bsR
Genotype axeA2,axeb2,axeC2, cnxA-[pBsr2-cnx],bsR
Phenotype blasticidin resistant, axenic, null mutant
Axenic Growth Y
Viable Spore Formation OK
References Müller-Taubenberger A, Lupas AN, Li H, Ecke M, Simmeth E, Gerisch G.
Calreticulin and calnexin in the endoplasmic reticulum are important for phagocytosis.
EMBO J.  (2001)  20(23)   6772-82  
[PubMed ID = 11726513]  [RRC reference
Fajardo M, Schleicher M, Noegel A, Bozzaro S, Killinger S, Heuner K, Hacker J, Steinert M.
Calnexin, calreticulin and cytoskeleton-associated proteins modulate uptake and growth of Legionella pneumophila in Dictyostelium discoideum.
Microbiology (Reading, Engl.)  (2004)  150(Pt 9)   2825-35  
[PubMed ID = 15347742]  [RRC reference
Other Information
Depositor DSC
Source G. Gerisch
Use Condition A
DSC DBS0236189
Remarks
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Sequence
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