Strain - Detail

NBRP ID S00005
Strain Name ptnA-
Strain Summary pten-
Strain Descriptor pten-
Systematic Name DBS0236830
Species Dictyostelium discoideum
Category Recombinant
Parental Strain AX2
Mutagenesis Method homologous recombination
Mutagenesis Detail BSR cassette in HincII site of PTEN genomic fragment (P195:P1614)
Associated Gene ptnA 
Foreign Gene bsR
Genotype axeA2,axeB2,axeC2,bsR,ptnA-[PTEN-BSR]
Phenotype agg-, axenic, blasticidin resistant, null mutant
Axenic Growth Y
Viable Spore Formation NO
References Uyeda TQ, Iwadate Y, Umeki N, Nagasaki A, Yumura S.
Stretching actin filaments within cells enhances their affinity for the myosin II motor domain.
PLoS One  (2011)  6(10)   e26200  
[PubMed ID = 22022566]  [RRC reference
Iijima M, Devreotes P.
Tumor suppressor PTEN mediates sensing of chemoattractant gradients.
Cell  (2002)  109(5)   599-610  
[PubMed ID = 12062103]  [RRC reference
Other Information originally deposited by Peter Devreotes to Dicty Stock Center
Depositor DSC
Source P. Devreotes
Use Condition A
DSC DBS0236830