Strain - Detail
| Request |
 |
|
|---|---|---|
| NBRP ID | S00005 | |
| Strain Name | ptnA- | |
| Strain Summary | pten- | |
| Strain Descriptor | pten- | |
| Systematic Name | DBS0236830 | |
| Species | Dictyostelium discoideum | |
| Category | Recombinant | |
| Parental Strain | AX2 | |
| Mutagenesis Method | homologous recombination | |
| Mutagenesis Detail | BSR cassette in HincII site of PTEN genomic fragment (P195:P1614) | |
| Associated Gene | ptnA | |
| Foreign Gene | bsR | |
| Genotype | axeA2,axeB2,axeC2,bsR,ptnA-[PTEN-BSR] | |
| Phenotype | agg-, axenic, blasticidin resistant, null mutant | |
| Axenic Growth | Y | |
| Viable Spore Formation | NO | |
| References |
Uyeda TQ, Iwadate Y, Umeki N, Nagasaki A, Yumura S.
Stretching actin filaments within cells enhances their affinity for the myosin II motor domain. PLoS One (2011) 6(10) e26200 [PubMed ID = 22022566] [RRC reference] Iijima M, Devreotes P. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell (2002) 109(5) 599-610 [PubMed ID = 12062103] [RRC reference] |
|
| Other Information | originally deposited by Peter Devreotes to Dicty Stock Center | |
| Depositor | DSC | |
| Position | ||
| Source | P. Devreotes | |
| Use Condition | A | |
| DSC | DBS0236830 | |
| Remarks | ||
| Images | ||
| Sequence | ||
